IGF1R (CD221) Antibodies

Antibodies that detect IGF1R (CD221) can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, Immunocytochemistry and ELISA. These antibodies target IGF1R (CD221) in Human, Mouse and Rat samples. Our IGF1R (CD221) polyclonal,... Antibodies that detect IGF1R (CD221) can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, Immunocytochemistry and ELISA. These antibodies target IGF1R (CD221) in Human, Mouse and Rat samples. Our IGF1R (CD221) polyclonal, monoclonal and recombinant monoclonal antibodies are... Antibodies that detect IGF1R (CD221) can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, Immunocytochemistry and ELISA. These antibodies target IGF1R (CD221) in Human, Mouse and Rat samples. Our IGF1R (CD221) polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. Find the IGF1R (CD221) antibody that fits your needs. Choose from 1 of 35 IGF1R (CD221) antibodies, which have been validated in experiments with 15 publications and 118 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been... Antibodies that detect IGF1R (CD221) can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, Immunocytochemistry and ELISA. These antibodies target IGF1R (CD221) in Human, Mouse and Rat samples. Our IGF1R (CD221) polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. Find the IGF1R (CD221) antibody that fits your needs. Choose from 1 of 35 IGF1R (CD221) antibodies, which have been validated in experiments with 15 publications and 118 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

IGF1R, also known as Insulin-like Growth Factor 1 (IGF-1) Receptor, is a receptor tyrosine kinase activated by IGF-1 and IGF-2. IGFR has been implicated in a variety of cancers. The protein is a tetramer consisting of two alpha, and two beta subunits. The alpha-subunits binds to insulin growth factor 1 with higher affinity than to insulin growth factor 2. Binding results in a conformational change, followed by autophosphorylation of IGF-1R at positions 1134, 1135, 1136. The activated IGF-1R in turn, causes phosphorylation of substrate proteins, followed by sequential activation of RAS, RAF, and mitogen-activated protein kinase isoforms ERK, p38, and JNK, leading to the transcription of genes that drive proliferation.

同义词

A330103N21Rik; CD221; CD221 antigen; D930020L01; hyft; IGF 1 receptor; IGF 1R; Igf1r; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

IGF1R (CD221) Antibodies

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